Abstract: Objective To scan significant clinicopathologic parameters in brainstem gliomas (BG) for outcome. Methods 54 cases with BG were reviewed and followed up. Results and Conclusion 41 cases were followed up. The main complaint included hoarseness and bucking, dizziness. The higher tumor grade, higher mitotic-index, necrosis of tumor, hyperplasy of blood vessel endothelium, Ki-67 index > 5% were associated with shorter survival. In opposite, Rosenthal fibers always presented in lower grade gliomas and associated with long survival.

Key words: gliomas, brainstem, outcome, pathology, Ki-67