Abstract: Periarticular heterotopic ossification (HO) is common complication after the injury to joint and central nervous system, which can lead to dysfunction of the involved joints. This article reviewed the literatures and discuss the complex nature of HO, including its pathophysiology, diagnosis, associated risk factors, and medical management. In particularly, an extensive literature review combined with author's clinical practice will serve as a foundation to understand the concepts regarding the management of HO and joints rehabilitation.

Key words: joint, heterotopic ossification, rehabilitation, review