Abstract: ObjectiveTo observe the psychological state in patients accepting prosthesis and the effect of psychological intervention on them. Methods38 patients were assessed with Symptom Checklist 90 (SCL-90) before, after prosthesis fitting, and after rehabilitation training and psychological intervention. ResultsThere were 33 cases with somehow disorder in some factors of SCL-90 before prosthesis fitting. Except somatization, interpersonal and psychotic factors, all the other factors increased after fitting （P<0.05）. All the factors scored lower after rehabilitation and intervention （P<0.05）. ConclusionPatients accepting prosthesis appear with some psychological disorders, and get worst after prosthesis fitting. Rehabilitation training and psychological intervention can relieve these disorders.

Key words: prosthesis, psychological intervention, rehabilitation, Symptom Checklist 90