Abstract: Objective To observe the effect of propofol combined with sufentanil in manipulation release on scapulohumeral periarthritis.Methods 62 patients with scapulohumeral periarthritis undergoing manipulation release were randomly assigned to propofol group(Group P) and propofol combined with sufentanil group (Group PS) with 31 cases in each group. Group P received 2 mg/kg dose of intravenouspropofol pre-operatively and Group PS received 2 mg/kg dose of intravenous propofol combined with sufentanil of which the loadingdose was 0.1 μg/kg and the basal rate was 0.1μg/kg/h pre-operatively. Repeated propofol could be used in both groups at the dose of 0.5 mg/kg. Blood pressure (BP), heart rate (HR), pulse oxygen saturation (SpO₂), pain on injection of propofol, level of anesthesia effect in operation,level of analgesia after operation, recovery time, and incidence of post-operative nausea and vomiting (PONV) were recorded. ResultsThe level of anesthesia effect in operation and the level of analgesia after operation were significantly higher in group PS (P<0.01). No painon injection of propofol was found in group PS. There was no significant difference in BP, HR, SpO₂, recovery time, and incidence of PONVbetween two groups (P<0.05). Conclusion Propofol combined with sufentanil can effectively improve the anesthesia effect in operation andthe analgesia after operation.

Key words: propofol, sufentanil, scapulohumeral periarthritis, manipulation release