Abstract: Objective To explore the activity of daily living in patients with schizophrenia and its related factors. Methods 200 patientswith schizophrenia were investigated with the questionnaire about general condition, the Positive and Negative Syndrome Scale (PANSS)and Activity of Daily Living Scale (ADL) when hospitalized. The relationship between the scores of ADL and sexuality, age, education level,marital status, profession before the disease attacking, household, disease type, course of the disease, frequency of attacking and hospitalizationor scores of PANSS was analyzed. Results The score of ADL was significantly above the normal level (t=32.206, P=0.000) in theschizophrenics. The score of ADL was not significantly different among the patients in different gender, education level, marital status, profession,household and the frequency of hospitalization (P>0.05), but was significantly different among the ages (F=3.851, P=0.023) and diseasetype (F=19.793, P=0.000). The score of ADL positively correlated with the course of the disease (r=0.161, P=0.023), frequency of attacking(r=0.396, P=0.000) and the difference value between the numbers of attacking and hospitalization (r=0.425, P=0.000), so as the totaland each factors scores of PANSS (P=0.000), but did not correlated with frequency of hospitalization (r= 0.097, P=0.174). By multiple regressionanalysis, only 3 factors score of PANSS, the frequency of attacking and the difference value between the numbers of attacking andhospitalization entered into the regression equation (F=53.630, P=0.000). Conclusion The patients with schizophrenia generally fall in activityof daily living. The more serious the disease, the more frequent the attacking and the more the difference value between the numbers ofattacking and hospitalization, the poorer the activity of daily living was.

Key words: schizophrenia, activity of daily living, related factors