《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2012, Vol. 18 ›› Issue (4): 329-330.

• 论文 • Previous Articles     Next Articles

Effects of Morroniside on Inhibiting Thromboxane B2 after Platelet Aggregation Induced by Adenosine Diphosphate in Rabbits

ZUO Wei, WANG Xiao-feng, AI Hou-xi, et al.   

  1. China Pharmaceutical University, Nanjing 210009, Jiangsu, China
  • Received:2011-08-05 Revised:1900-01-01 Published:2012-04-25 Online:2012-04-25

Abstract: Objective To study the effects of morroniside on thromboxane B2 in the condition of platelet aggregation in rabbits inducedby adenosine diphosphate (ADP). Methods The level of TXB2 was determined by enzyme-linked immunosorbent assay (ELISA). ResultsCompared with the controls, morroniside significantly inhibited the increase of TXB2 induced by ADP (P<0.001). Conclusion Morronisidecan inhibit the level of TXB2 by inhibiting the platelet aggregation in rabbits induced by ADP.

Key words: morroniside, platelet aggregation, thromboxane B2, rabbits