Abstract: Frailty is a physiological state of nonspecific vulnerability to stressors resulting from decreased physiological reserves and the deregulation of multiple physiological systems associated with advancing age. Frailty is more than an association with specific diseases or disabilities, but rather a systemic manifestation of physical and cognitive deficits, including signs, symptoms, illnesses, and impairments, that accumulate over the life course. This paper reviewed the studies illustrating the concept, evaluation, risk factor and application of frailty on rehabilitation.

Key words: frailty, elderly, frailty index, review