Abstract: Motor dysfunction is one of the leading problems after stroke. The evidence existed that motor performance is largely affected by the location and volume of white matter especially the pyramidal tract, but not the cortex. The remodeling of contralesional primary motor output tract highly correlated with motor improvement. The unaffected pyramidal tract axons regenerate and cross into the affected side after ischemia can promte motor recovery after ischemia. Exercise and other rehabilitation may play a role on remodeling of pyramidal tract subsequent after cerebral infarction.

Key words: cerebral ischemia, pyramidal tract, motor, rehabilitation, review