Abstract: Objective To observe the effect of 3R therapy on quality of life and subjective well-being in older patients with mild cognitive impairment (MCI). Methods 158 patients with MCI were collected from 8 communities in Ningbo city with Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV as the diagnostic criteria, and assessed by Montreal Cognitive Assessment (MoCA). The experimental group (n=79) was intervened by 3R (Reminiscence, Reality Orientation, Remotivation) for 12 weeks, and the control group (n=79) received no intervention. Their quality of life was assessed with WHO Quality of Life-BREF (WHOQOL-BREF) and the subjective well-being was assessed with Philadelphia Geriatric Center Morale Scale (PGC). Results Their quality of life and subjective well-being improved after intervention in the experimental group (P<0.05), and were better in the experimental group than in the control group (P<0.05). Conclusion 3R therapy could effectively improve the quality of life and subjective well-being in patients with MCI.

Key words: mild cognitive impairment, 3R therapy, quality of life, subjective well-being