Abstract: Corticospinal tract (CST) is the major neuronal pathway that mediates voluntary movements. This article reviewed the literature related to the role of the CST in motor recovery in stroke patients with respect to the following: recovery of a damaged CST, perilesional reorganization at the subcortical level, perilesional reorganization at the cortex level, the ipsilateral motor pathway from the affected hemisphere to the affected extremities, and locomotor recovery.

Key words: stroke, corticospinal tract, motor recovery, hemiplegia, review