《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2015, Vol. 21 ›› Issue (03): 292-295.

• 综述 • Previous Articles     Next Articles

Role of Mitogen-activated Protein Kinases Signaling Pathway in Development of Osteoarthritis (review)

LI Sheng-cun, WANG Guo-xiang   

  1. School of Physical Education of Soochow University, Suzhou, Jiangsu 215021, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2015-03-25 Online:2015-03-25

Abstract: Osteoarthritis (OA) is a common disease among elders and athletes. Mitogen-activated protein kinases (MAPKs) are molecules of stress sensitivity which play a significant role in the occurrence and development of OA. MAPKs are closely related with chondrocyte apoptosis and cartilage degradation. This paper reviewed the related studies between OA and MAPKs.

Key words: mitogen-activated protein kinases, osteoarthritis, stress, review