CJRTP

《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2015, Vol. 21 ›› Issue (04): 378-381.

• 专题 • Previous Articles     Next Articles

Advance in Mechanism of Brain Remodeling Induced by Spinal Cord Injury (review)

FENG Dong-liang1,2, ZHANG Hai-hong2, WU Ya-min1
   

  1. 1. Department 3 of Research Institute of Surgery, Daping Hospital, Third Military Medical University, State Key Laboratory of Trauma, Burns and Combined Injury, Chongqing 400042, China; 2. Department of Orthopedics, Second Clinical Medical College of Lanzhou University, Lanzhou, Gansu 730030, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2015-04-25 Online:2015-04-25

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Abstract: In recent decades, with the development of electrophysiological and neuroimaging techniques, the researchers found that spinal cord injury (SCI) not only caused pathological changes in the spinal cord, but also in the brain. This paper reviewed the influence of SCI on the structure and function of the brain in terms of brain neuron degeneration caused by SCI, the changes of neurotrophic factor in brain, and the side-effects of medicine.

Key words: spinal cord injury, brain injury, neurotrophic factor, function remodeling, review