Abstract: Objective To establish a coupled model combining the rat brain nuclei microelectrode recordings and the behavioristics for rehabilitation experiment. Methods The modified indwelling tube connection fixed device was put inside the rats' back, and the microprobes were implanted into related neural nucleus. A signal connection was made between self-administration system and electrophysiological data acquisition system. The rat was addicted after training by self-administration system. The related cerebral nucleus electrophysiological signals were recorded in different states of addiction. Results and Conclusion The modified indwelling tube connection fixed device has a better quality for reducing the phenomenon of leak. The signal was well in the combination of two different systems. The signals for the rat's action and neural electrical were recorded in the same time.

Key words: microprobe recording, self-administration, cerebral function, rehabilitation, neurophysiology