1999年至2025年脊髓电刺激治疗脊髓损伤研究的文献计量分析

doi:10.3969/j.issn.1006-9771.2026.04.001

Abstract

Abstract:

Objective To analyze the research hotspots and development trends in the field of spinal cord stimulation (SCS) for spinal cord injury (SCI).

Methods Literature about SCS for SCI was retrieve from the Web of Science (WOS) Core Collection database, with a time range from January, 1999 to July, 2025. VOSviewer 1.6.20 and CiteSpace 6.4.R2 were used to analyze the annual publication volume, countries, authors, institutions, journals and keywords.

Results A total of 636 literatures were included. From 1999 to 2025, the overall publication trend in this field showed an upward trajectory, with recent years fluctuating but tending to stabilize. The country with the most publications was the United States (429 papers), followed by Russia (98 papers) and China (70 papers). The institution with the highest number of publications was the University of California, Los Angeles (76 papers), the author with the most publications was V. Reggie Edgerton (70 papers), and the journal with the most publications was Journal of Clinical Medicine (31 papers). The most frequently cited study focused on exploring the combination of epidural spinal cord stimulation with task-specific training to restore motor function in patients with complete SCI. Keyword analysis showed that the research hotspots in this field were mainly focused on neuroregulation mechanisms, recovery of motor and autonomic nervous dysfunction, artificial intelligence, closed-loop stimulation and brain-computer interface technology innovations. In recent years, the research focus gradually shifted from basic mechanisms to personalized and precise multifunctional rehabilitation strategies.

Conclusion The field of SCS for SCI has undergone phases of basic mechanism exploration and clinical application expansion. Current research hotspots and future trends focus primarily on the development of new stimulation paradigms and combined innovative technologies.

Key words: spinal cord injury, spinal cord stimulation, bibliometrics

CLC Number:

R651.2

QI Yuanyuan, GAO Haifeng, LIU Lina, XIE Yujie, XU Jing, GAO Feng, CHEN Liang, YANG Degang, LI Jun. Spinal cord stimulation for spinal cord injury from 1999 to 2025: a bibliometric analysis[J]. Chinese Journal of Rehabilitation Theory and Practice, 2026, 32(4): 373-386.

Figures/Tables 17

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Table 7

Keyword clusters and related keywords"

聚类号	标签	LLR聚类代表关键词
#0	spinal cord stimulation	spinal cord stimulation、electrode、column stimulation、neurostimulation、neuropathic pain、back surgery syndrome、dorsal horn neurons、spinal reflexes、autonomic reflex pathway、cortical excitability
#1	motor recovery	motor recovery、functional recovery、hand function、gait、neural plasticity、circuit reorganization、pattern generators、interlimb coordination、motor training
#2	artificial intelligence	artificial intelligence、system、guidelines、strategy、classification、computational simulation
#3	lower limb	lower limb、soleus H reflex、leg muscles、reflex、reciprocal inhibition、muscle strength、motor rehabilitation、fatigue、voluntary movement
#4	dysfunction	dysfunction、neurogenic bladder、external urethral sphincter、neural control、dysesthetic pain、lower urinary tract、back pain
#5	modulation	modulation、activity-dependent plasticity、stimulation、motor control、pattern、volitional control、corticospinal tract
#6	cough	restore cough、expiratory muscles、cervical spinal cord、high-frequency stimulation、current density、BDNF
#7	autonomic function	autonomic function、cardiovascular function、bowel management、autonomic dysreflexia、orthostatic hypotension
#8	respiratory muscles	respiratory muscles、abdominal muscles、contractile property、mechanical insufflation exsufflation、airway pressure、tetraplegic subjects
#9	spinal cord	spinal cord、cord dorsum potentials、spinally evoked motor potentials、spasticity、epidural spinal stimulation
#10	diaphragm pacing	diaphragm pacing、diaphragm、intercostal muscles、phrenic nerve、respiratory paralysis、motor complete paraplegia、contusion injury、inspiratory muscles、intermittent hypoxia、cervical cord
#11	functional electrical stimulation	functional electrical stimulation、dorsal column stimulation、central pattern generator、intraspinal microstimulation、bladder contractions、locomotion、assistive technology、dynamic contractions
#12	spinal cord injury	spinal cord injury、neuromodulation、bladder control、detrusor hyperreflexia、electric stimulation therapy、araplegia、conditional stimulation、afferents
#13	interneurons	Interneurons、fictive locomotion、control of movement、circuits、lumbar cord、afferent stimulation、spatiotemporal neuromodulation、axon regeneration
#14	brain-computer interfaces	brain-computer interfaces、EEG、implantation、functional restoration、ambulation、motoneurons

Table 7

Figure 9

Figure 10

References 64

[1]	刘宏炜. 创伤性脊柱脊髓损伤诊断与治疗专家共识(2022版)[J]. 中国老年保健医学, 2022, 20(4): 6-9.
	LIU H W. Expert consensus on diagnosis and treatment of traumatic spinal cord injury (2022 edition) [J]. Chin J Geriatr Care, 2022, 20(4): 6-9.
[2]	LU Y, SHANG Z, ZHANG W, et al. Global incidence and characteristics of spinal cord injury since 2000-2021: a systematic review and meta-analysis [J]. BMC Med, 2024, 22(1): 285. doi: 10.1186/s12916-024-03514-9 pmid: 38972971
[3]	张浩, 刘宇, 肖世宁, 等. 中国创伤性脊髓损伤患者流行病学特征的Meta分析[J]. 中国脊柱脊髓杂志, 2023, 33(5): 397-407.
	ZHANG H, LIU Y, XIAO S N, et al. Epidemiological characteristics of traumatic spinal cord injury in China: a meta-analysis[J]. Chin J Spine Spinal Cord, 2023, 33(5): 397-407.
[4]	陈星月, 陈栋, 陈春慧, 等. 中国创伤性脊髓损伤流行病学和疾病经济负担的系统评价[J]. 中国循证医学杂志, 2018, 18(2): 143-150.
	CHEN X Y, CHEN D, CHEN C H, et al. Epidemiology and economic burden of traumatic spinal cord injury in China: a systematic review[J]. Chin J Evidence-Based Med, 2018, 18(2): 143-150.
[5]	邓亮强, 刘震洋, 牛剑平, 等. 脊髓电刺激对脊髓损伤治疗的研究进展[J]. 国际神经病学神经外科学杂志, 2024, 51(6): 75-81.
	DENG L Q, LIU Z Y, NIU J P, et al. Research progress on spinal cord stimulation for the treatment of spinal cord injury[J]. J Int Neurol Neurosurg, 2024, 51(6): 75-81.
[6]	DOOLEY D M, SHARKEY J, KELLER W, et al. Treatment of demyelinating and degenerative diseases by electro stimulation of the spinal cord[J]. Med Prog Technol, 1978, 6(1): 1-14. pmid: 310508
[7]	MELZACK R, WALL P D. Pain mechanisms: a new theory[J]. Science, 1965, 150(3699): 971-979. doi: 10.1126/science.150.3699.971 pmid: 5320816
[8]	SHEALY C N, MORTIMER J T, ESWICK J B. Electrical inhibition of pain by stimulation of the dorsal columns: preliminary clinical report[J]. Anesth Analg, 1967, 46(4): 489-491. pmid: 4952225
[9]	BAROLAT G, MYKLEBUST J B, WENNINGER W. Enhancement of voluntary motor function following spinal cord stimulation: case study[J]. Appl Neurophysiol, 1986, 49(6): 307-314.
[10]	BROADUS R N. Toward a definition of "bibliometrics"[J]. Scientometrics, 1987, 12(5): 373-379. doi: 10.1007/BF02016680
[11]	HARKEMA S, GERASIMENKO Y, HODES J, et al. Effect of epidural stimulation of the lumbosacral spinal cord on voluntary movement, standing, and assisted stepping after motor complete paraplegia: a case study[J]. Lancet, 2011, 377(9781): 1938-1947. doi: 10.1016/S0140-6736(11)60547-3 pmid: 21601270
[12]	ANGELI C A, EDGERTON V R, GERASIMENKO Y P, et al. Altering spinal cord excitability enables voluntary movements after chronic complete paralysis in humans[J]. Brain, 2014, 137(Pt 5): 1394-1409. doi: 10.1093/brain/awu038 pmid: 24713270
[13]	ANGELI C A, BOAKYE M, MORTON R A, et al. Recovery of over-ground walking after chronic motor complete spinal cord injury[J]. N Engl J Med, 2018, 379(13): 1244-1250. doi: 10.1056/NEJMoa1803588
[14]	WAGNER F B, MIGNARDOT J B, LE GOFF-MIGNARDOT C G, et al. Targeted neurotechnology restores walking in humans with spinal cord injury[J]. Nature, 2018, 563(7729): 65-71. doi: 10.1038/s41586-018-0649-2
[15]	GILL M L, GRAHN P J, CALVERT J S, et al. Neuromodulation of lumbosacral spinal networks enables independent stepping after complete paraplegia[J]. Nat Med, 2018, 24(11): 1677-1682. doi: 10.1038/s41591-018-0175-7 pmid: 30250140
[16]	章沿锋, 蔡世宏, 柳成江, 等. 国产脊髓电刺激系统在小尾寒羊植入的长期安全性和组织相容性研究[J]. 中国疼痛医学杂志, 2024, 30(8): 568-577.
	ZHANG Y F, CAI S H, LIU C J, et al. Long-term safety and histocompatibility of a domestically produced spinal cord stimulation system implanted in small-tailed Han sheep[J]. Chin J Pain Med, 2024, 30(8): 568-577.
[17]	AYANWUYI L, TOKARSKA N, MCLEAN N A, et al. Brief electrical nerve stimulation enhances intrinsic repair capacity of the focally demyelinated central nervous system[J]. Neural Regen Res, 2022, 17(5): 1042-1050. doi: 10.4103/1673-5374.324848 pmid: 34558531
[18]	HAHM S C, YOON Y W, KIM J. High-frequency transcutaneous electrical nerve stimulation alleviates spasticity after spinal contusion by inhibiting activated microglia in rats[J]. Neurorehabil Neural Repair, 2015, 29(4): 370-381. doi: 10.1177/1545968314545172
[19]	HACHMANN J T, YOUSAK A, WALLNER J J, et al. Epidural spinal cord stimulation as an intervention for motor recovery after motor complete spinal cord injury[J]. J Neurophysiol, 2021, 126(6): 1843-1859. doi: 10.1152/jn.00020.2021 pmid: 34669485
[20]	MORAUD E M, CAPOGROSSO M, FORMENTO E, et al. Mechanisms underlying the neuromodulation of spinal circuits for correcting gait and balance deficits after spinal cord injury[J]. Neuron, 2016, 89(4): 814-828. doi: 10.1016/j.neuron.2016.01.009 pmid: 26853304
[21]	GREINER N, BARRA B, SCHIAVONE G, et al. Recruitment of upper-limb motoneurons with epidural electrical stimulation of the cervical spinal cord[J]. Nat Commun, 2021, 12(1): 435. doi: 10.1038/s41467-020-20703-1 pmid: 33469022
[22]	CHALIF J I, CHAVARRO V S, MENSAH E, et al. Epidural spinal cord stimulation for spinal cord injury in humans: a systematic review[J]. J Clin Med, 2024, 13(4): 1090. doi: 10.3390/jcm13041090
[23]	CAPOGROSSO M, WAGNER F B, GANDAR J, et al. Configuration of electrical spinal cord stimulation through real-time processing of gait kinematics[J]. Nat Protoc, 2018, 13(9): 2031-2061. doi: 10.1038/s41596-018-0030-9 pmid: 30190556
[24]	MINASSIAN K, PERSY I, RATTAY F, et al. Human lumbar cord circuitries can be activated by extrinsic tonic input to generate locomotor-like activity[J]. Hum Mov Sci, 2007, 26(2): 275-295. doi: 10.1016/j.humov.2007.01.005
[25]	BERTRAND S, CAZALETS J R. The respective contribution of lumbar segments to the generation of locomotion in the isolated spinal cord of newborn rat[J]. Eur J Neurosci, 2002, 16(9): 1741-1750. pmid: 12431227
[26]	SHAPKOVA E Y, SCHOMBURG E D. Two types of motor modulation underlying human stepping evoked by spinal cord electrical stimulation (SCES)[J]. Acta Physiol Pharmacol Bulg, 2001, 26(3): 155-157. pmid: 11695529
[27]	FORMENTO E, MINASSIAN K, WAGNER F, et al. Electrical spinal cord stimulation must preserve proprioception to enable locomotion in humans with spinal cord injury[J]. Nat Neurosci, 2018, 21(12): 1728-1741. doi: 10.1038/s41593-018-0262-6 pmid: 30382196
[28]	ASBOTH L, FRIEDLI L, BEAUPARLANT J, et al. Cortico-reticulo-spinal circuit reorganization enables functional recovery after severe spinal cord contusion[J]. Nat Neurosci, 2018, 21(4): 576-588. doi: 10.1038/s41593-018-0093-5 pmid: 29556028
[29]	SEÁÑEZ I, CAPOGROSSO M. Motor improvements enabled by spinal cord stimulation combined with physical training after spinal cord injury: review of experimental evidence in animals and humans[J]. Bioelectron Med, 2021, 7(1): 16. doi: 10.1186/s42234-021-00077-5
[30]	KUMAR K, TOTH C, NATH R K, et al. Improvement of limb circulation in peripheral vascular disease using epidural spinal cord stimulation: a prospective study[J]. J Neurosurg, 1997, 86(4): 662-669. pmid: 9120631
[31]	PIEDADE G S, VESPER J, REICHSTEIN D, et al. Spinal cord stimulation in non-reconstructable critical limb ischemia: a retrospective study of 71 cases[J]. Acta Neurochir, 2023, 165(4): 967-973. doi: 10.1007/s00701-022-05448-8
[32]	KLINKOVA A, KAMENSKAYA O, ASHURKOV A, et al. The clinical outcomes in patients with critical limb ischemia one year after spinal cord stimulation[J]. Ann Vasc Surg, 2020, 62: 356-364. doi: S0890-5096(19)30171-2 pmid: 30802587
[33]	MANNHEIMER C, ELIASSON T, AUGUSTINSSON L E, et al. Electrical stimulation versus coronary artery bypass surgery in severe angina pectoris: the ESBY study[J]. Circulation, 1998, 97(12): 1157-1163. pmid: 9537342
[34]	CUI J G, LINDEROTH B, MEYERSON B A. Effects of spinal cord stimulation on touch-evoked allodynia involve GABAergic mechanisms. An experimental study in the mononeuropathic rat [J]. Pain, 1996, 66(2/3): 287-295. doi: 10.1016/0304-3959(96)03069-2
[35]	SONG Z, MEYERSON B A, LINDEROTH B. Spinal 5-HT receptors that contribute to the pain-relieving effects of spinal cord stimulation in a rat model of neuropathy[J]. Pain, 2011, 152(7): 1666-1673. doi: 10.1016/j.pain.2011.03.012 pmid: 21514998
[36]	MATTIE R, LIN A B, BHANDAL H, et al. Spinal cord stimulation for the treatment of complex regional pain syndrome: a systematic review of randomized controlled trials[J]. Interv Pain Med, 2024, 3(4): 100527.
[37]	HOIKKANEN T, NISSEN M, IKÄHEIMO T M, et al. Long-term outcome of spinal cord stimulation in complex regional pain syndrome[J]. Neurosurgery, 2021, 89(4): 597-609. doi: 10.1093/neuros/nyab239 pmid: 34245150
[38]	COURTINE G, GERASIMENKO Y, VAN DEN BRAND R, et al. Transformation of nonfunctional spinal circuits into functional states after the loss of brain input[J]. Nat Neurosci, 2009, 12(10): 1333-1342. doi: 10.1038/nn.2401 pmid: 19767747
[39]	ROWALD A, KOMI S, DEMESMAEKER R, et al. Activity-dependent spinal cord neuromodulation rapidly restores trunk and leg motor functions after complete paralysis[J]. Nat Med, 2022, 28(2): 260-271. doi: 10.1038/s41591-021-01663-5 pmid: 35132264
[40]	MORITZ C, FIELD-FOTE E C, TEFERTILLER C, et al. Non-invasive spinal cord electrical stimulation for arm and hand function in chronic tetraplegia: a safety and efficacy trial[J]. Nat Med, 2024, 30(5): 1276-1283. doi: 10.1038/s41591-024-02940-9 pmid: 38769431
[41]	SCHIEFERDECKER S, NEUDORFER C, EL MAJDOUB F, et al. A retrospective case series of high-frequency spinal cord stimulation (HF10-SCS) in neurogenic bladder incontinence[J]. Oper Neurosurg, 2019, 17(1): 14-20. doi: 10.1093/ons/opy236 pmid: 30169840
[42]	ZANDER H J, KOWALSKI K E, DIMARCO A F, et al. Model-based optimization of spinal cord stimulation for inspiratory muscle activation[J]. Neuromodulation, 2022, 25(8): 1317-1329. doi: 10.1111/ner.13415
[43]	LEGG DITTERLINE B E, ASLAN S C, WANG S, et al. Restoration of autonomic cardiovascular regulation in spinal cord injury with epidural stimulation: a case series[J]. Clin Auton Res, 2021, 31(2): 317-320. doi: 10.1007/s10286-020-00693-2
[44]	SQUAIR J W, GAUTIER M, MAHE L, et al. Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury[J]. Nature, 2021, 590(7845): 308-314. doi: 10.1038/s41586-020-03180-w
[45]	FLETT S, GARCIA J, COWLEY K C. Spinal electrical stimulation to improve sympathetic autonomic functions needed for movement and exercise after spinal cord injury: a scoping clinical review[J]. J Neurophysiol, 2022, 128(3): 649-670. doi: 10.1152/jn.00205.2022 pmid: 35894427
[46]	NIGHTINGALE T E, WALTER M, WILLIAMS A M M, et al. Ergogenic effects of an epidural neuroprosthesis in one individual with spinal cord injury[J]. Neurology, 2019, 92(7): 338-340. doi: 10.1212/WNL.0000000000006923 pmid: 30635485
[47]	MALONE I G, KELLY M N, NOSACKA R L, et al. Closed-loop, cervical, epidural stimulation elicits respiratory neuroplasticity after spinal cord injury in freely behaving rats[J]. eNeuro, 2022, 9(1): ENEURO.426-21.2021..
[48]	ZHANG T, JIA Y, WANG N, et al. Recent advances in potential mechanisms of epidural spinal cord stimulation for movement disorders[J]. Exp Neurol, 2025, 392: 115330. doi: 10.1016/j.expneurol.2025.115330
[49]	LAM C M, LATIF U, SACK A, et al. Advances in spinal cord stimulation[J]. Bioengineering, 2023, 10(2): 185. doi: 10.3390/bioengineering10020185
[50]	KAPURAL L, YU C, DOUST M W, et al. Novel 10-kHz high-frequency therapy (HF10 therapy) is superior to traditional low-frequency spinal cord stimulation for the treatment of chronic back and leg pain: the SENZA-RCT randomized controlled trial[J]. Anesthesiology, 2015, 123(4): 851-860. doi: 10.1097/ALN.0000000000000774 pmid: 26218762
[51]	KAPURAL L, YU C, DOUST M W, et al. Comparison of 10-kHz high-frequency and traditional low-frequency spinal cord stimulation for the treatment of chronic back and leg pain: 24-month results from a multicenter, randomized, controlled pivotal trial[J]. Neurosurgery, 2016, 79(5): 667-677. pmid: 27584814
[52]	DEER T, SLAVIN K V, AMIRDELFAN K, et al. Success using neuromodulation with BURST (SUNBURST) study: results from a prospective, randomized controlled trial using a novel burst waveform[J]. Neuromodulation, 2018, 21(1): 56-66. doi: 10.1111/ner.12698 pmid: 28961366
[53]	CAYLOR J, REDDY R, YIN S, et al. Spinal cord stimulation in chronic pain: evidence and theory for mechanisms of action[J]. Bioelectron Med, 2019, 5(1): 12. doi: 10.1186/s42234-019-0023-1
[54]	RUSSO M, BROOKER C, COUSINS M J, et al. Sustained long-term outcomes with closed-loop spinal cord stimulation: 12-month results of the prospective, multicenter, open-label avalon study[J]. Neurosurgery, 2020, 87(4): E485-E495.
[55]	MEKHAIL N, LEVY R M, DEER T R, et al. Long-term safety and efficacy of closed-loop spinal cord stimulation to treat chronic back and leg pain (Evoke): a double-blind, randomised, controlled trial[J]. Lancet Neurol, 2020, 19(2): 123-134. doi: S1474-4422(19)30414-4 pmid: 31870766
[56]	SAMEJIMA S, KHORASANI A, RANGANATHAN V, et al. Brain-computer-spinal interface restores upper limb function after spinal cord injury[J]. IEEE Trans Neural Syst Rehabil Eng, 2021, 29: 1233-1242. doi: 10.1109/TNSRE.2021.3090269
[57]	LORACH H, GALVEZ A, SPAGNOLO V, et al. Walking naturally after spinal cord injury using a brain-spine interface[J]. Nature, 2023, 618(7963): 126-133. doi: 10.1038/s41586-023-06094-5
[58]	FLESHER S N, DOWNEY J E, WEISS J M, et al. A brain-computer interface that evokes tactile sensations improves robotic arm control[J]. Science, 2021, 372(6544): 831-836. doi: 10.1126/science.abd0380 pmid: 34016775
[59]	JASZCZUK P, BRATELJ D, CAPONE C, et al. Advances in neuromodulation and digital brain-spinal cord interfaces for spinal cord injury[J]. Int J Mol Sci, 2025, 26(13): 6021. doi: 10.3390/ijms26136021
[60]	HAGEDORN J M, GEORGE T K, AIYER R, et al. Artificial intelligence and pain medicine: an introduction[J]. J Pain Res, 2024, 17: 509-518. doi: 10.2147/JPR.S429594 pmid: 38328019
[61]	PRUNSKIS J V, MASYS T, PYLES S T, et al. The application of artificial intelligence to enhance spinal cord stimulation efficacy for chronic pain management: current evidence and future directions[J]. Curr Pain Headache Rep, 2025, 29(1): 85. doi: 10.1007/s11916-025-01400-4
[62]	ESTES S, ZARKOU A, HOPE J M, et al. Combined transcutaneous spinal stimulation and locomotor training to improve walking function and reduce spasticity in subacute spinal cord injury: a randomized study of clinical feasibility and efficacy[J]. J Clin Med, 2021, 10(6): 1167. doi: 10.3390/jcm10061167
[63]	EDGERTON V R, COURTINE G, GERASIMENKO Y P, et al. Training locomotor networks[J]. Brain Res Rev, 2008, 57(1): 241-254. doi: 10.1016/j.brainresrev.2007.09.002 pmid: 18022244
[64]	LI L, ZHANG B, ZHAO W, et al. Multimodal technologies for closed-loop neural modulation and sensing[J]. Adv Healthc Mater, 2024, 13(24): e2303289.

排名	国家	发文量/n	被引量	平均被引量	连接强度
1	美国	429	18997	44.28	334
2	俄罗斯	98	8380	85.51	167
3	中国	70	1642	23.46	57
4	英国	62	3950	63.71	122
5	加拿大	58	2096	36.14	78

排名	机构	发文量/n	被引量	平均被引量	连接强度
1	University of California, Los Angeles	76	7296	96.00	148
2	University of Louisville	57	3411	59.84	73
3	Pavlov Institute of Physiology	52	6775	130.29	120
4	Case Western Reserve University	36	778	21.61	29
5	Mayo Clinic	36	1121	31.14	55

排名	作者	国家	机构	发文量/n	被引量	平均被引量	H指数	连接强度
1	V. Reggie Edgerton	美国	Ranchos Los Amigos National Rehabilitation Center	70	6608	94.40	108	241
2	Yury Gerasimenko	美国	Pavlov Institute of Physiology	57	6002	105.30	7	198
3	Susan J. Harkema	美国	University of Louisville	44	3206	72.86	50	81
4	Igor Lavrov	美国	Mayo Clinic	36	2413	67.03	27	115
5	Roland R. Roy	美国	University of California, Los Angeles	36	3083	85.64	85	140

排名	期刊	发文量/n	被引量	平均被引量	IF	JCR
1	Journal of Clinical Medicine	31	350	11.29	2.9	Q1
2	Frontiers in Neuroscience	26	555	21.35	3.2	Q2
3	Journal of Neurophysiology	26	886	34.08	2.1	Q3
4	Experimental Neurology	21	571	27.19	4.2	Q1
5	IEEE Transactions on Neural Systems and Rehabilitation Engineering	21	735	35.00	5.2	Q1

排名	作者	年份	题名	期刊	被引频次	连接强度
1	Susan J. Harkema等^[11]	2011	Effect of epidural stimulation of the lumbosacral spinal cord on voluntary movement, standing, and assisted stepping after motor complete paraplegia: a case study	The Lancet	281	2696
2	Claudia A. Angeli等 ^[12]	2014	Altering spinal cord excitability enables voluntary movements after chronic complete paralysis in humans	Brain	204	2259
3	Claudia A. Angeli等^[13]	2018	Recovery of over-ground walking after chronic motor complete spinal cord injury	New England Journal of Medicine	159	1855
4	Fabien B. Wagner等^[14]	2018	Targeted neurotechnology restores walking in humans with spinal cord injury	Nature	157	1770
5	Megan L. Gill等^[15]	2018	Neuromodulation of lumbosacral spinal networks enables independent stepping after complete paraplegia	Nature Medicine	150	1785

Spinal cord stimulation for spinal cord injury from 1999 to 2025: a bibliometric analysis

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排名	关键词	出现频次	平均频次
1	spinal cord injury	436	36.61
2	spinal cord stimulation	389	38.78
3	neuromodulation	214	36.55
4	functional recovery	169	43.79
5	electrical stimulation	161	34.25

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