儿童脊髓损伤后脊髓萎缩的MRI特征以及与损伤平面的相关性

doi:10.3969/j.issn.1006-9771.2026.04.002

Abstract

Abstract:

Objective To delineate imaging findings using an imaging platform and investigate the correlation between MRI characteristics of spinal cord atrophy and clinical diagnosis in children with spinal cord injury (SCI).

Methods Imaging data of 150 children with SCI admitted to Beijing Bo'ai Hospital, China Rehabilitation Research Center, from January, 2002 to March, 2024 were collected and imported into the imaging platform. The anteroposterior and transverse diameters of the middle part of the spinal cord at the cross-section with the most severe atrophy were measured, and the relevant indicators of the previous normal spinal cord segment were measured as controls; the radiomic features were extracted. Clinical data of the children including gender, age, cause of injury, sensory level, motor level, spinal cord injury level, injury severity and disease course were collected.

Results Spinal cord atrophy was identified in 81 cases (54%), among which 78 cases (96%) were American Spinal Injury Association Impairment Scale (AIS) grade A and 3 cases (4%) were AIS grade C. The upper boundary of the spinal cord atrophy site strongly correlated with the injury level, motor level and sensory level (r > 0.8, P < 0.001).

Conclusion More than half of children with SCI may develop secondary spinal cord atrophy, the vast majority of whom suffer from complete spinal cord injury; the upper boundary of spinal cord atrophy is correlated with the injury level.

Key words: spinal cord injury, children, spinal cord atrophy, injury level, radiomics

CLC Number:

R651.2

ZHANG Yingxin, LIU Genlin, CHEN Di, ZHANG Hongxia, TIAN Yifan, WANG Yiji, JING Yang, CHENG Ruidong, ZHANG Shaomin, YAO Jiafeng, SUN Bo, SUN Xiaomeng. MRI findings of spinal cord atrophy after spinal cord injury in children and their injury level[J]. Chinese Journal of Rehabilitation Theory and Practice, 2026, 32(4): 387-392.

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References 20

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赋值	ISNCSCI平面	脊髓萎缩上限
1	C₁	C₁
2	C₂	C₂
3	C₃	C₃
4	C₄	C₄
5	C₅	C₅
6	C₆	C₆
7	C₇	C₇
8	C₈	T₁
9	T₁	T₂
10	T₂	T₃
11	T₃	T₄
12	T₄	T₅
13	T₅	T₆
14	T₆	T₇
15	T₇	T₈
16	T₈	T₉
17	T₉	T₁₀
18	T₁₀	T₁₁
19	T₁₁	T₁₂
20	T₁₂	L₁
21	L₁	L₂
22	L₂	L₃
23 24 25 26 27 28 29	L₃ L₄ L₅ S₁ S₂ S₃ S_4-5	L₄ L₅ S₁ S₂ S₃ S_4-5

病程	n
< 1个月	1
1~< 3个月	40
3~< 6个月	21
6~< 12个月	13
≥ 12个月	6

平面	n	平面	n
C₃	1	T₅	6
C₄	1	T₆	11
C₅	4	T₇	9
C₆	6	T₈	26
C₇	6	T₉	49
T₁	6	T₁₀	59
T₂	5	T₁₁	53
T₃	3	T₁₂	27
T₄	4	L₁	9

基本特征		萎缩	无萎缩	χ²值	P值
受伤年龄	< 8岁	61	45	1.830	0.176
受伤年龄	≥ 8岁	20	24		0.176
性别	男	16	17	0.518	0.472
性别	女	65	52		0.472
病因	外伤	63	53	0.020	0.888
病因	非外伤	18	16		0.888

变量	C_3-7	T_1-4	T_5-8	T_9-12
脊髓萎缩上限	5.2	9.3	15.1	16.3
损伤平面	5.0	10.0	16.0	18.0

MRI findings of spinal cord atrophy after spinal cord injury in children and their injury level

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