CJRTP

Chinese Journal of Rehabilitation Theory and Practice >

2016 , Vol. 22 >Issue 7: 824 - 826

DOI: https://doi.org/10.3969/j.issn.1006-9771.2016.07.019

Changes of Serum S-100β Protein after Complete Spinal Cord Injury

  • WANG Yu- ming1 ,
  • 2 ,
  • ZHU Zhi- min3 ,
  • CHE Jun- yan1 ,
  • 2 ,
  • LI Hui- lan1 ,
  • 2 ,
  • MA Ke1 ,
  • 2 ,
  • GONG Hui- ming1 ,
  • 2 ,
  • CHEN Hui1 ,
  • 2 ,
  • ZHONG Hua3 ,
  • YANG Ming-liang1 ,
  • 2 ,
  • DU Liang-jie1 ,
  • 2
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  • 1. Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing 100068, China; 2. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China; 3. The Lianjiang People's Hospital, Lianjiang, Guangdong 524400, China

Online published: 2016-09-22

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Abstract

Objective To evaluate whether S-100β protein could be a serum marker for traumatic spinal cord injury (SCI). Methods From June, 2013 to October, 2014, 24 patients with complete SCI were measured the serum S- 100β protein concentrations with enzyme- linked immunosorbent assay, one week, three and six months after SCI. Serum from ten healthy persons was as normal control. Results The serum S-100β protein concentrations increased one week and 3 months after SCI (Z>4.273, P<0.001). Conclusion The increase of serum S-100β protein may help assessing early impairment after complete SCI.

Key words： spinal cord injury; S-100&beta; protein; serum; biomarker

Cite this article

WANG Yu- ming1 , 2 , ZHU Zhi- min3 , CHE Jun- yan1 , 2 , LI Hui- lan1 , 2 , MA Ke1 , 2 , GONG Hui- ming1 , 2 , CHEN Hui1 , 2 , ZHONG Hua3 , YANG Ming-liang1 , 2 , DU Liang-jie1 , 2 . Changes of Serum S-100β Protein after Complete Spinal Cord Injury[J]. Chinese Journal of Rehabilitation Theory and Practice, 2016 , 22(7) : 824 -826 . DOI: 10.3969/j.issn.1006-9771.2016.07.019

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