Impairment of Weight Support of Lower Limbs after Spinal Cord Hemi-section in Rhesus Monkeys

  • ZHAO Wen ,
  • WEI Rui-han ,
  • RAO Jia-sheng ,
  • ZHAO Can ,
  • TIAN Peng-yu ,
  • ZHOU Xia ,
  • JI Run ,
  • LI Li-feng ,
  • YANG Zhao-yang ,
  • LI Xiao-guang
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  • 1. Department of Neurobiology, Capital Medical University, Beijing 100069, China;
    2. Beijing Key Laboratory for Biomaterials and Neural Regeneration, Department of Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China;
    3. Human Biomechanics Laboratory, National Research Center for Rehabilitation Technical Aids, Beijing 100176, China

Received date: 2017-11-13

  Revised date: 2017-12-07

  Online published: 2018-03-27

Supported by

Supported by National Key Research and Development Program (No. 2017YFC1104002; No. 2017YFC1104001); National Natural Science Foundation of China, Key Program (No. 31730030), General Program (No. 31670988; No. 31771053), Emergency Management Program (No. 31650001), Projects of International Cooperation and Exchanges (No. 31320103903); Special Funds for the Authors of Excellent Doctoral Dissertations of Universities and Colleges (No. 201356); and Beijing Science and Technology Program (No. Z171100002217066)

Abstract

Objective To observe the influence of spinal cord injury on lower limbs weight support capacity, and the changes with time. Methods Six adult female rhesus monkeys with thoracic (T7-9) right spinal cord hemi-section were measured the plantar pressure ratio of both lower limbs with Foot-Scan system before, and six and twelve weeks after operation. Results There was no statistical difference between both sides of limbs before operation (Z=-1.330, P>0.05), while the plantar pressure ratio was more on the left limbs six and twelve weeks after operation (Z>4.783, P<0.001). The plantar pressure ratio of right lower limb became less and less during observation (Z=3.191, P<0.001).Conclusion The weight support capacity of affected limbs is injured after spinal cord hemi-section in monkeys, and would become worse without intervention.

Cite this article

ZHAO Wen , WEI Rui-han , RAO Jia-sheng , ZHAO Can , TIAN Peng-yu , ZHOU Xia , JI Run , LI Li-feng , YANG Zhao-yang , LI Xiao-guang . Impairment of Weight Support of Lower Limbs after Spinal Cord Hemi-section in Rhesus Monkeys[J]. Chinese Journal of Rehabilitation Theory and Practice, 2018 , 24(3) : 266 -268 . DOI: 10.3969/j.issn.1006-9771.2017.00.001

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