Evaluation for Parkinson's Disease with Chinese Version of MDS-UPDRS and Original UPDRS

  • QU Yan ,
  • LI Xiao-hong ,
  • SUN Ya-nan ,
  • LI Ya-hui
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  • Dalian Friendship Hospital, Dalian, Liaoning 116001, China

Received date: 2019-05-22

  Revised date: 2019-06-16

  Online published: 2019-08-16

Supported by

Supported by Dalian Medical Science Research Project (No. 1611029)

Abstract

Objective To evaluate the reliability and validity of Chinese version of International Parkinson and Movement Disorder Society (MDS)-Unified Parkinson's Disease Rating Scale (UPDRS), and then do comparative analysis with original UPDRS. Methods From May, 2016 to December, 2018, 225 patients with Parkinson's disease were respectively evaluated by MDS-UPDRS and UPDRS, and then the reliability and validity of MDS-UPDRS were evaluated. Correlation between two scales was analyzed. Results The Cronbach's coefficient of the total MDS-UPDRS was 0.734. Rank correlation's coefficient was 0.905. For factor analysis, KMO was 0.728. Pearson's correlation analysis showed that the correlation's coefficient of the common factor of the two scales was 0.969, while the correlation's coefficient of the total score of the two scales was 0.972. Compared with UPDRS, MDS-UPDRS added a number of non-motor symptoms, which adjusted the standard of measurement and increased the accuracy degree of evaluation at early stage of disease. Besides, MDS-UPDRS added a lot of instructions to evaluate the standards to make the evaluation normatively. Conclusion Chinese version of MDS-UPDRS has high reliability and validity, and highly correlate with the original UPDRS. It is more suitable for Chinese patients with Parkinson's disease in clinical evaluation than UPDRS.

Cite this article

QU Yan , LI Xiao-hong , SUN Ya-nan , LI Ya-hui . Evaluation for Parkinson's Disease with Chinese Version of MDS-UPDRS and Original UPDRS[J]. Chinese Journal of Rehabilitation Theory and Practice, 2019 , 25(8) : 936 -939 . DOI: 10.3969/j.issn.1006-9771.2019.08.010

References

1 Martinez-MartinP, Rodriguez-BlazquezC, Alvarez-SanchezM, et al. Expanded and independent validation of the Movement Disorder Society-Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) [J]. J Neurol, 2013, 260(1): 228-236.
2 AntoniniA, AbbruzzeseG, Ferini-StrambiL, et al. Validation of the Italian version of the Movement Disorder Society-Unified Parkinson’s Disease Rating Scale [J]. Neurol Sci, 2013, 34(5): 683-687.
3 KashiharaK, KondoT, MizunoY, et al. Official Japanese Version of the Movement Disorder Society-Unified Parkinson’s Disease Rating Scale: validation against the original English version [J]. Mov Disord Clin Pract, 2014, 1(3): 200-212.
4 AkbostanciM C, BayramE, YilmazV, et al. Turkish Standardization of Movement Disorders Society Unified Parkinson's Disease Rating Scale and Unified Dyskinesia Rating Scale [J]. Mov Disord Clin Pract, 2017, 5(1): 54-59.
5 ZitserJ, PeretzC, Ber DavidA, et al. Validation of the Hebrew version of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale [J]. Parkinsonism Relat Disord, 2017, 45: 7-12.
6 中华医学会神经病学分会帕金森病及运动障碍学组,中国医师协会神经内科医师分会帕金森病及运动障碍专业. 中国帕金森病的诊断标准(2016版)[J]. 中华神经科杂志, 2016, 49(4): 268-271.
7 GoetzC G, PoeweW, RascolO, et al. The Unified Parkinson's Disease Rating Scale (UPDRS): status and recommendations [J]. Mov Disord, 2003, 18(7): 738-750.
8 GoetzC G, TilleyB C, ShaftmanS R, et al. Movement Disorder Society-Sponsored Revision of the Unified Parkinson’s Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results [J]. Mov Disord, 2008, 23(15): 2129-2170.
9 LangA E, EberlyS, GoetzC G, et al. Movement disorder society unified Parkinson disease rating scale experiences in daily living: longitudinal changes and correlation with other assessments [J]. Mov Disord, 2013, 28(14): 1980-1986.
10 Rodriguez-BlazquezC, Rojo-AbuinJ M, Alvarez-SanchezM, et al. The MDS-UPDRS Part II (motor experiences of daily living) resulted useful for assessment of disability in Parkinson's disease [J]. Parkinsonism Relat Disord, 2013, 19(10): 889-893.
11 RacitiL, NicolettiA, MostileG, et al. Accuracy of MDS-UPDRS section IV for detecting motor fluctuations in Parkinson's disease [J]. Neurol Sci, 2019, 40(6): 1271-1273.
12 Martinez-MartinP, Rodriguez-BlazguezC, AlvarezMario, et al. Parkinson's disease severity levels and MDS-Unified Parkinson's Disease Rating Scale [J]. Parkinsonism Relat Disord, 2015, 21(1): 50-54.
13 RegnaultA, BoroojerdiB, MeunierJ, et al. Does the MDS-UPDRS provide the precision to assess progression in early Parkinson's disease? Learnings from the Parkinson's progression marker initiative cohort [J]. J Neurol, 2019, 266(8): 1927-1936.
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