Abstract: Objective To investigate the relationship between the neonatal period hyperbilirubinemia and dyskinetic cerebral palsy.Methods The data of 36 dyskinetic cerebral palsy children with early neonatal period significant jaundice were analyzed retrospectively. The information of children was obtained through a questionnaire that included the case, severing clinical characteristics and treatment.Results 12 cases (33.33%) were born with hemolytice disease of newborn; 8 cases (22.2%) were born with early onset infection; 5 cases (13.9%) were born with cephalohematome; others were unknown etiologies. 6 cases had serum total bilirubin (TSB) value more than 600 μmol/L (the highest value was 792 μmol/L); 12 cases had TSB value ranged from 513 μmol/L to 600 μmol/L; 14 cases had TSB value ranged from 425 μmol/L to 512 μmol/L; 2 cases had TSB value lower than 425 μmol/L (the lowest value was 396 μmol/L). 2 cases had no TSB data. The time of jaundice significantly turned severer was 156±12.56 hours after birth. The time of jaundice continued was 23±5.62 days after birth. 34 cases had been diagnosed and treated. But the first treatment time of all were later 150 hours after birth.Conclusion As the main risk factor of dyskinetic cerebral palsy, severe hyperbilirubinemia need be valued. How to ease bilirubin quickly in the early stage is much important.

Key words: cerebral palsy, dyskinetic, early jaundice