《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2012, Vol. 18 ›› Issue (8): 710-712.

• 论文 • Previous Articles     Next Articles

Study on Event-Related Potential N400 for Chinese Aphasia Patients

ZHOU Liang, YE Xiang-ming, LI Jue-bao, et al   

  1. Department of Rehabilitation Medicine, Zhejiang Provincial People's Hospital, Hangzhou 310014, Zhejiang, China
  • Received:2012-05-10 Revised:2012-07-14 Published:2012-08-25 Online:2012-08-25

Abstract: Objective To investigate the feature of event-related potential N400 for Chinese aphasia patients. Methods 23 Chinese aphasia patients and 20 controls were evaluated with Western Aphasia Battery (WAB), and N400 was also measured. Results N400 latency was longer and N400 amplitude was higher in the aphasia group than in the control group. In aphasia group, the latency (r=-0.553, P=0.000) and amplitude of N400 (r=-0.628, P=0.000) correlated to the score of Aphasia Quotient (AQ), and the amplitude of N400 correlated to the score of anomia in WAB (r=-0.372, P=0.001). Conclusion Event-related potential N400 could reflect the level of language function impairment and it is a valuable index for evaluating language function, especially anomia level in Chinese aphasia patients

Key words: Chinese, aphasia, event-related potential, N400