上肢康复机器人辅助训练对脑卒中患者上肢功能的效果：基于功能性近红外光谱

doi:10.3969/j.issn.1006-9771.2023.11.012

Abstract

Abstract:

Objective To study the effect of upper limb robot-assisted therapy on upper limb function and cerebral cortex activation in stroke patients using functional near-infrared spectroscopy (fNIRS).

Methods From January, 2022 to January, 2023, 32 stroke patients in Zhejiang Rehabilitation Medical Center were randomly divided into control group (n = 16) and experimental group (n = 16). Both groups received routine neurological medication and routine rehabilitation. The control group received routine upper limb exercises, the experimental group received upper limb robot-assisted therapy. They were assessed with Fugl-Meyer Assessment-Upper Extremities (FMA-UE) and fNIRS (oxyhemoglobin, deoxyhemoglobin, and total hemoglobin) before and four weeks after treatment. NIRS_SPM was used for activation analysis, Homer2 was used for blood oxygen concentration analysis.

Results After treatment, the score of FMA-UE increased in both groups (|t| > 5.910, P < 0.001), and was higher in the experimental group than in the control group (t= -2.348, P < 0.05). fNIRS activation results showed that, the activation increased in the experimental group after treatment in channel 17 (F= 9.354, P < 0.01), and it was more than that in the control group (F = 5.217, P < 0.05). fNIRS blood oxygen concentration results showed that, the blood oxygen concentration increased in the experimental group after treatment in channel 17 (F = 12.179, P < 0.01), and it was more than that in the control group (F = 4.883, P < 0.05).

Conclusion The upper limb robot-assisted therapy can improve the upper limb motor function and cerebral cortex activation of stroke patients.

Key words: stroke, upper limb, rehabilitation robot, functional near-infrared spectroscopy, cerebral cortex

CLC Number:

R743.3

SONG Jianfei, DAI Lei, QIN Zhengyuan, ZHANG Yan, GU Xinlu, CHEN Yanhong, LI Dongyue, FENG Xiaojuan. Effect of upper limb robot-assisted therapy on upper limb function in stroke patients: based on functional near-infrared spectroscopy[J]. Chinese Journal of Rehabilitation Theory and Practice, 2023, 29(11): 1339-1345.

Figures/Tables 6

组别	n	性别(男/女)/n	年龄/岁	病程/月	卒中类型(出血/梗死)/n	受损半球(左/右)/n
对照组	16	10/6	53.56 $±$ 13.02	3.38 $±$ 1.89	7/9	7/9
试验组	16	12/4	57.00 $±$ 13.85	3.75 $±$ 2.05	8/8	9/7
χ²/t值		0.582	-0.723	-0.538	0.125	0.500
P值		0.446	0.475	0.595	0.723	0.480

References 28

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组别	n	治疗前	治疗后	t值	P值
对照组	16	27.1±15.5	36.6±17.3	-6.090	< 0.001
试验组	16	31.7±14.1	47.8±8.0	-5.910	< 0.001
t值		-0.881	-2.348
P值		0.365	0.029

组别	n	治疗前	治疗后	F值	P值
对照组	16	0.006±0.005	0.006±0.004	0.029	0.865
试验组	16	0.005±0.005	0.009±0.001	9.354	0.005
F值		4.167	5.217
P值		0.050	0.030

组别	n	治疗前	治疗后	F值	P值
对照组	16	0.459±0.054	0.480±0.293	0.033	0.858
试验组	16	0.459±0.113	0.915±0.636	12.179	0.002
F值		0.000	4.883
P值		0.998	0.038

Effect of upper limb robot-assisted therapy on upper limb function in stroke patients: based on functional near-infrared spectroscopy

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